{"id":2026,"date":"2025-12-24T13:40:38","date_gmt":"2025-12-24T13:40:38","guid":{"rendered":"https:\/\/haema-journal.gr\/?p=2026"},"modified":"2025-12-24T15:07:27","modified_gmt":"2025-12-24T15:07:27","slug":"%cf%83%cf%8d%ce%bd%ce%b4%cf%81%ce%bf%ce%bc%ce%bf-%cf%85%cf%80%ce%b5%cf%81%ce%b1%ce%b9%ce%bc%cf%8c%ce%bb%cf%85%cf%83%ce%b7%cf%82","status":"publish","type":"post","link":"https:\/\/haema-journal.gr\/?p=2026","title":{"rendered":"\u03a3\u03cd\u03bd\u03b4\u03c1\u03bf\u03bc\u03bf \u03a5\u03c0\u03b5\u03c1\u03b1\u03b9\u03bc\u03cc\u03bb\u03c5\u03c3\u03b7\u03c2"},"content":{"rendered":"<p style=\"text-align: right;\"><em>Haema 2025; 16(1):25-26<\/em><\/p>\n<p>\u0395\u03c5\u03c6\u03c1\u03bf\u03c3\u03cd\u03bd\u03b7 \u039d\u03bf\u03bc\u03b9\u03ba\u03bf\u03cd<\/p>\n<p>\u0391\u03b9\u03bc\u03b1\u03c4\u03bf\u03bb\u03cc\u03b3\u03bf\u03c2, \u0394\u03b9\u03b5\u03c5\u03b8\u03cd\u03bd\u03c4\u03c1\u03b9\u03b1 \u039d\u03a5 \u0391\u03b9\u03bc\u03bf\u03b4\u03bf\u03c3\u03af\u03b1\u03c2, \u03a4\u03bc\u03ae\u03bc\u03b1 \u0394\u03b9\u03b1\u03c4\u03b1\u03c1\u03b1\u03c7\u03ce\u03bd \u03c4\u03b7\u03c2 \u03a0\u03ae\u03be\u03b7\u03c2 \u03ba\u03b1\u03b9 \u0391\u03b9\u03bc\u03bf\u03c1\u03c1\u03bf\u03c6\u03b9\u03bb\u03b9\u03ba\u03ce\u03bd \u0391\u03c3\u03b8\u03b5\u03bd\u03ce\u03bd, \u0393\u039d\u0391 \u00ab\u0399\u03c0\u03c0\u03bf\u03ba\u03c1\u03ac\u03c4\u03b5\u03b9\u03bf\u00bb<\/p>\n<p>&nbsp;<\/p>\n<p style=\"text-align: right;\"><a href=\"https:\/\/haema-journal.gr\/wp-content\/uploads\/2025\/12\/Haema-16-25.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Full PDF<\/a> | <a href=\"https:\/\/haema-journal.gr\/wp-content\/uploads\/2025\/12\/Haema-16-25.pdf\" target=\"_blank\" rel=\"noopener noreferrer\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-390 size-full\" src=\"https:\/\/haema-journal.gr\/wp-content\/uploads\/2018\/02\/PDF-icon.jpg\" alt=\"\" width=\"36\" height=\"36\" \/><\/a><\/p>\n<p><!--more--><\/p>\n<p style=\"text-align: justify;\"><strong>\u0391\u03bb\u03bb\u03b7\u03bb\u03bf\u03b3\u03c1\u03b1\u03c6\u03af\u03b1:<\/strong> \u0395\u03c5\u03c6\u03c1\u03bf\u03c3\u03cd\u03bd\u03b7 \u039d\u03bf\u03bc\u03b9\u03ba\u03bf\u03cd, \u0391\u03b9\u03bc\u03b1\u03c4\u03bf\u03bb\u03cc\u03b3\u03bf\u03c2, \u0394\u03b9\u03b5\u03c5\u03b8\u03cd\u03bd\u03c4\u03c1\u03b9\u03b1 \u039d\u03a5 \u0391\u03b9\u03bc\u03bf\u03b4\u03bf\u03c3\u03af\u03b1\u03c2, \u03a4\u03bc\u03ae\u03bc\u03b1 \u0394\u03b9\u03b1\u03c4\u03b1\u03c1\u03b1\u03c7\u03ce\u03bd \u03c4\u03b7\u03c2 \u03a0\u03ae\u03be\u03b7\u03c2 \u03ba\u03b1\u03b9 \u0391\u03b9\u03bc\u03bf\u03c1\u03c1\u03bf\u03c6\u03b9\u03bb\u03b9\u03ba\u03ce\u03bd \u0391\u03c3\u03b8\u03b5\u03bd\u03ce\u03bd, \u0393\u039d\u0391 \u00ab\u0399\u03c0\u03c0\u03bf\u03ba\u03c1\u03ac\u03c4\u03b5\u03b9\u03bf\u00bb, E-mail: efrosyni.nomikou@gmail.com<\/p>\n<hr \/>\n<h5 style=\"text-align: justify;\"><strong>\u0395\u0399\u03a3\u0391\u0393\u03a9\u0393\u0397<\/strong><\/h5>\n<p style=\"text-align: justify;\">\u03a4\u03bf \u03c3\u03cd\u03bd\u03b4\u03c1\u03bf\u03bc\u03bf \u03a5\u03c0\u03b5\u03c1\u03b1\u03b9\u03bc\u03cc\u03bb\u03c5\u03c3\u03b7\u03c2 \u03c3\u03c5\u03bd\u03b9\u03c3\u03c4\u03ac \u03bc\u03b9\u03b1 \u03c3\u03c0\u03ac\u03bd\u03b9\u03b1 \u03b1\u03bb\u03bb\u03ac \u03c3\u03bf\u03b2\u03b1\u03c1\u03ae \u03b5\u03c0\u03b9\u03c0\u03bb\u03bf\u03ba\u03ae \u03c3\u03c7\u03b5\u03c4\u03b9\u03b6\u03cc\u03bc\u03b5\u03bd\u03b7 \u03bc\u03b5 \u03bc\u03b5\u03c4\u03ac\u03b3\u03b3\u03b9\u03c3\u03b7. \u03a0\u03b1\u03c1\u03b1\u03c4\u03b7\u03c1\u03b5\u03af\u03c4\u03b1\u03b9 \u03ba\u03c5\u03c1\u03af\u03c9\u03c2 \u03c3\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 \u03b4\u03c1\u03b5\u03c0\u03b1\u03bd\u03bf\u03ba\u03c5\u03c4\u03c4\u03b1\u03c1\u03b9\u03ba\u03ae \u03bd\u03cc\u03c3\u03bf, \u03b1\u03bd \u03ba\u03b1\u03b9 \u03ad\u03c7\u03b5\u03b9 \u03c0\u03b5\u03c1\u03b9\u03b3\u03c1\u03b1\u03c6\u03b5\u03af \u03c3\u03c0\u03b1\u03bd\u03af\u03c9\u03c2 \u03ba\u03b1\u03b9 \u03c3\u03b5 \u03ac\u03bb\u03bb\u03bf\u03c5\u03c2 \u03c0\u03bf\u03bb\u03c5\u03bc\u03b5\u03c4\u03b1\u03b3\u03b3\u03b9\u03b6\u03cc\u03bc\u03b5\u03bd\u03bf\u03c5\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03cc\u03c0\u03c9\u03c2 \u03c0\u03ac\u03c3\u03c7\u03bf\u03bd\u03c4\u03b5\u03c2 \u03b1\u03c0\u03cc \u03bc\u03b5\u03c3\u03bf\u03b3\u03b5\u03b9\u03b1\u03ba\u03ae \u03b1\u03bd\u03b1\u03b9\u03bc\u03af\u03b1 \u03ae\u00a0 \u03c3\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 \u03ac\u03bb\u03bb\u03b1 \u03b1\u03b9\u03bc\u03b1\u03c4\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ac \u03bd\u03bf\u03c3\u03ae\u03bc\u03b1\u03c4\u03b1.<\/p>\n<p style=\"text-align: justify;\">\u03a7\u03b1\u03c1\u03b1\u03ba\u03c4\u03b7\u03c1\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b1\u03c7\u03b5\u03af\u03b1 \u03b1\u03b9\u03bc\u03cc\u03bb\u03c5\u03c3\u03b7 \u03c4\u03cc\u03c3\u03bf \u03c4\u03c9\u03bd \u03b5\u03c1\u03c5\u03b8\u03c1\u03ce\u03bd \u03c4\u03bf\u03c5 \u03b1\u03c3\u03ba\u03bf\u03cd, \u03cc\u03c3\u03bf \u03ba\u03b1\u03b9 \u03c4\u03c9\u03bd \u03b1\u03c5\u03c4\u03cc\u03bb\u03bf\u03b3\u03c9\u03bd \u03b5\u03c1\u03c5\u03b8\u03c1\u03ce\u03bd \u03c0\u03bf\u03c5 \u03bf\u03b4\u03b7\u03b3\u03b5\u03af \u03c3\u03b5 \u03b4\u03c5\u03c3\u03b1\u03bd\u03ac\u03bb\u03bf\u03b3\u03b7 \u03b1\u03bd\u03b1\u03b9\u03bc\u03af\u03b1\u00a0 \u03bc\u03b5 \u03c0\u03c4\u03ce\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03b1\u03b9\u03bc\u03bf\u03c3\u03c6\u03b1\u03b9\u03c1\u03af\u03bd\u03b7\u03c2\u00a0 \u03c4\u03bf\u03c5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03bf\u03cd\u03c2 \u03c3\u03b5 \u03c4\u03b9\u03bc\u03ad\u03c2 \u03c7\u03b1\u03bc\u03b7\u03bb\u03cc\u03c4\u03b5\u03c1\u03b5\u03c2 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03c4\u03b9\u03bc\u03ae\u00a0 \u03c0\u03c1\u03bf \u03c4\u03b7\u03c2 \u03bc\u03b5\u03c4\u03ac\u03b3\u03b3\u03b9\u03c3\u03b7\u03c2.<\/p>\n<p style=\"text-align: justify;\">\u0397 \u03c0\u03b1\u03b8\u03bf\u03b3\u03ad\u03bd\u03b5\u03b9\u03b1 \u03c4\u03bf\u03c5 \u03c3\u03c5\u03bd\u03b4\u03c1\u03cc\u03bc\u03bf\u03c5 \u03b4\u03b5\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03c0\u03bf\u03bb\u03cd\u03c4\u03c9\u03c2 \u03b3\u03bd\u03c9\u03c3\u03c4\u03ae. \u03a0\u03b9\u03b8\u03b1\u03bd\u03cc\u03c4\u03b5\u03c1\u03bf\u03b9 \u03bc\u03b7\u03c7\u03b1\u03bd\u03b9\u03c3\u03bc\u03bf\u03af \u03b8\u03b5\u03c9\u03c1\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9<\/p>\n<ul style=\"text-align: justify;\">\n<li>\u03b7 \u03b5\u03bd\u03b5\u03c1\u03b3\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03c3\u03c5\u03bc\u03c0\u03bb\u03b7\u03c1\u03ce\u03bc\u03b1\u03c4\u03bf\u03c2 \u03b5\u03c0\u03af \u03c4\u03b7\u03c2 \u03bc\u03b5\u03bc\u03b2\u03c1\u03ac\u03bd\u03b7\u03c2 \u03c4\u03c9\u03bd \u03b5\u03c1\u03c5\u03b8\u03c1\u03ce\u03bd \u03c4\u03bf\u03c5 \u03b1\u03c3\u03ba\u03bf\u03cd \u03b1\u03bb\u03bb\u03ac \u03ba\u03b1\u03b9 \u03c4\u03c9\u03bd \u03b1\u03c5\u03c4\u03cc\u03bb\u03bf\u03b3\u03c9\u03bd \u03b5\u03c1\u03c5\u03b8\u03c1\u03ce\u03bd (\u03b5\u03af\u03c4\u03b5 \u03b1\u03c0\u03cc \u03b1\u03bb\u03bb\u03bf\u03b1\u03bd\u03c4\u03b9\u03c3\u03c9\u03bc\u03b1\u03c4\u03b1 \u03ad\u03bd\u03b1\u03bd\u03c4\u03b9 \u03b5\u03c1\u03c5\u03b8\u03c1\u03bf\u03ba\u03c5\u03c4\u03c4\u03b1\u03c1\u03b9\u03ba\u03ce\u03bd \u03b7 HLA\u00a0 \u03b1\u03bd\u03c4\u03b9\u03b3\u03cc\u03bd\u03c9\u03bd \u03b1\u03c0\u03cc \u03c0\u03c1\u03bf\u03b7\u03b3\u03bf\u03cd\u03bc\u03b5\u03bd\u03b7 \u03bc\u03b5\u03c4\u03ac\u03b3\u03b3\u03b9\u03c3\u03b7, \u03b5\u03af\u03c4\u03b5 \u03b1\u03c0\u03cc \u03b1\u03c5\u03c4\u03bf\u03b1\u03bd\u03c4\u03b9\u03c3\u03ce\u03bc\u03b1\u03c4\u03b1).<\/li>\n<li>\u03c5\u03c0\u03b5\u03c1-\u03b4\u03c1\u03b1\u03c3\u03c4\u03b7\u03c1\u03b9\u03bf\u03c4\u03b7\u03c4\u03b1 \u0394\u0395\u03a3 .<\/li>\n<li>\u03b7 \u03b1\u03bd\u03b1\u03b4\u03b9\u03ac\u03c4\u03b1\u03be\u03b7 \u03c4\u03c9\u03bd \u03c6\u03c9\u03c3\u03c6\u03bf\u03bb\u03b9\u03c0\u03b9\u03b4\u03af\u03c9\u03bd \u03c4\u03b7\u03c2 \u03bc\u03b5\u03bc\u03b2\u03c1\u03ac\u03bd\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03b7 \u03ad\u03ba\u03c6\u03c1\u03b1\u03c3\u03b7 \u03c4\u03b7\u03c2 PS (\u03c6\u03c9\u03c3\u03c6\u03b1\u03c4\u03b9\u03b4\u03c5\u03bb\u03c3\u03b5\u03c1\u03b9\u03bd\u03b7\u03c2) \u03c3\u03c4\u03b7\u03bd \u03b5\u03c0\u03b9\u03c6\u03ac\u03bd\u03b5\u03b9\u03b1 \u03c4\u03c9\u03bd \u03b5\u03c1\u03c5\u03b8\u03c1\u03bf\u03ba\u03c5\u03c4\u03c4\u03ac\u03c1\u03c9\u03bd \u03c4\u03cc\u03c3\u03bf \u03c4\u03bf\u03c5 \u03b1\u03c3\u03ba\u03bf\u03cd (\u03bf\u03be\u03b5\u03b9\u03b4\u03c9\u03c4\u03b9\u03ba\u03ae \u03b2\u03bb\u03ac\u03b2\u03b7 \u03ba\u03b1\u03c4\u03ac \u03c4\u03b7\u03bd \u03c6\u03cd\u03bb\u03b1\u03be\u03b7) \u03cc\u03c3\u03bf \u03ba\u03b1\u03b9 \u03c4\u03c9\u03bd \u03b1\u03c5\u03c4\u03cc\u03bb\u03bf\u03b3\u03c9\u03bd \u03b5\u03c1\u03c5\u03b8\u03c1\u03ce\u03bd(\u03b4\u03c1\u03b5\u03c0\u03b1\u03bd\u03bf\u03ba\u03cd\u03c4\u03c4\u03b1\u03c1\u03b1) \u03bf\u03b4\u03b7\u03b3\u03b5\u03af \u03c3\u03c4\u03b7\u03bd \u03c6\u03b1\u03b3\u03bf\u03ba\u03c5\u03c4\u03c4\u03ac\u03c1\u03c9\u03c3\u03b7 \u03b1\u03c0\u03cc \u03c4\u03b1 \u03bc\u03b1\u03ba\u03c1\u03bf\u03c6\u03ac\u03b3\u03b1.<\/li>\n<li>\u03ba\u03b1\u03c4\u03b1\u03c3\u03c4\u03bf\u03bb\u03ae \u03c4\u03b7\u03c2 \u03b5\u03c1\u03c5\u03b8\u03c1\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7\u03c2 (\u03b1\u03c0\u03cc \u03c4\u03b7 \u03bc\u03b5\u03c4\u03ac\u03b3\u03b3\u03b9\u03c3\u03b7 \u03b7 \u03bb\u03b1\u03bd\u03b8\u03ac\u03bd\u03bf\u03c5\u03c3\u03b1 \u03bb\u03bf\u03af\u03bc\u03c9\u03be\u03b7 \u03b7 \u03bd\u03b5\u03c6\u03c1\u03b9\u03ba\u03ae \u03b2\u03bb\u03ac\u03b2\u03b7).<\/li>\n<li>\u0393\u03b5\u03bd\u03b5\u03c4\u03b9\u03ba\u03ae \u03c0\u03c1\u03bf\u03b4\u03b9\u03ac\u03b8\u03b5\u03c3\u03b7<em> (\u03bc\u03b5\u03c4\u03b1\u03bb\u03bb\u03ac\u03be\u03b5\u03b9\u03c2 <\/em><em>MBL2, <\/em><em>KLCR3)<\/em><\/li>\n<\/ul>\n<p style=\"text-align: justify;\">\u0397 \u03b1\u03bb\u03b7\u03b8\u03ae\u03c2 \u03b5\u03c0\u03af\u03c0\u03c4\u03c9\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03c3\u03c5\u03bd\u03b4\u03c1\u03cc\u03bc\u03bf\u03c5 \u03b4\u03b5\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03b3\u03bd\u03c9\u03c3\u03c4\u03ae, \u03b5\u03be\u03b1\u03b9\u03c4\u03af\u03b1\u03c2 \u03c4\u03b7\u03c2 \u03c3\u03c0\u03b1\u03bd\u03b9\u03cc\u03c4\u03b7\u03c4\u03b1\u03c2 \u03b1\u03bb\u03bb\u03ac \u03ba\u03b1\u03b9 \u03c4\u03b7\u03c2 \u03b1\u03c3\u03c4\u03bf\u03c7\u03af\u03b1\u03c2 \u03c3\u03c4\u03b7 \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7 \u03b7 \u03c3\u03c4\u03b7 \u03ba\u03b1\u03c4\u03b1\u03b3\u03c1\u03b1\u03c6\u03ae \u03c4\u03c9\u03bd \u03c0\u03c1\u03b1\u03b3\u03bc\u03b1\u03c4\u03b9\u03ba\u03ce\u03bd \u03b5\u03c0\u03b5\u03b9\u03c3\u03bf\u03b4\u03af\u03c9\u03bd \u03c5\u03c0\u03b5\u03c1\u03b1\u03b9\u03bc\u03cc\u03bb\u03c5\u03c3\u03b7\u03c2. \u03a6\u03b1\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03c9\u03c3\u03c4\u03cc\u03c3\u03bf \u03cc\u03c4\u03b9 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c3\u03c5\u03c7\u03bd\u03cc\u03c4\u03b5\u03c1\u03bf \u03c3\u03c4\u03bf\u03c5\u03c2 \u03c0\u03b1\u03b9\u03b4\u03b9\u03b1\u03c4\u03c1\u03b9\u03ba\u03bf\u03cd\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2.<\/p>\n<h5 style=\"text-align: justify;\"><strong>\u0394\u0399\u0391\u0393\u039d\u03a9\u03a3\u0397<\/strong><\/h5>\n<p style=\"text-align: justify;\"><strong>\u039a\u03bb\u03b9\u03bd\u03b9\u03ba\u03ac \u03ba\u03c1\u03b9\u03c4\u03ae\u03c1\u03b9\u03b1<\/strong><\/p>\n<p style=\"text-align: justify;\"><em><strong>1 \u03ad\u03c9\u03c2 20 \u03b7\u03bc\u03ad\u03c1\u03b5\u03c2 \u03bc\u03b5\u03c4\u03ac \u03c4\u03b7\u03bd \u03bc\u03b5\u03c4\u03ac\u03b3\u03b3\u03b9\u03c3\u03b7:<\/strong><\/em><\/p>\n<ul style=\"text-align: justify;\">\n<li>\u03a3\u03c5\u03bc\u03c0\u03c4\u03c9\u03bc\u03b1\u03c4\u03bf\u03bb\u03bf\u03b3\u03af\u03b1 <em>\u03c3\u03bf\u03b2\u03b1\u03c1\u03ae\u03c2 \u03b1\u03bd\u03b1\u03b9\u03bc\u03af\u03b1\u03c2 \u03bc\u03b5 \u03c3\u03c4\u03bf\u03b9\u03c7\u03b5\u03af\u03b1 \u03b1\u03b9\u03bc\u03cc\u03bb\u03c5\u03c3\u03b7\u03c2 (\u03c0\u03c5\u03c1\u03b5\u03c4\u03cc\u03c2- \u03af\u03ba\u03c4\u03b5\u03c1\u03bf\u03c2).<\/em><\/li>\n<li>\u0391\u03b9\u03bc\u03bf\u03c3\u03c6\u03b1\u03b9\u03c1\u03b9\u03bd\u03bf\u03c5\u03c1\u03af\u03b1<\/li>\n<li>\u0395\u03c0\u03ce\u03b4\u03c5\u03bd\u03bf\u03c2 \u03ba\u03c1\u03af\u03c3\u03b7 \u03c3\u03b5 \u03b4\u03c1\u03b5\u03c0\u03b1\u03bd\u03bf\u03ba\u03c5\u03c4\u03c4\u03b1\u03c1\u03b9\u03ba\u03bf\u03cd\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2\u00a0 \u03ba\u03bf\u03bd\u03c4\u03ac \u03c3\u03b5 \u03bc\u03b5\u03c4\u03ac\u03b3\u03b3\u03b9\u03c3\u03b7 \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03c0\u03ac\u03bd\u03c4\u03b1 \u03bd\u03b1 \u03b4\u03b9\u03b5\u03c1\u03b5\u03c5\u03bd\u03ac\u03c4\u03b1\u03b9 \u03b3\u03b9\u03b1 \u03c3\u03cd\u03bd\u03b4\u03c1\u03bf\u03bc\u03bf \u03c5\u03c0\u03b5\u03c1\u03b1\u03b9\u03bc\u03cc\u03bb\u03c5\u03c3\u03b7\u03c2.<\/li>\n<li>\u039c\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03c3\u03c5\u03bd\u03bf\u03b4\u03b5\u03cd\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc\u00a0 \u03bf\u03be\u03cd \u03b8\u03c9\u03c1\u03b1\u03ba\u03b9\u03ba\u03cc \u03c3\u03cd\u03bd\u03b4\u03c1\u03bf\u03bc\u03bf, \u03ba\u03b1\u03c1\u03b4\u03b9\u03b1\u03ba\u03ae \u03b1\u03bd\u03b5\u03c0\u03ac\u03c1\u03ba\u03b5\u03b9\u03b1, \u03c0\u03b1\u03b3\u03ba\u03c1\u03b5\u03b1\u03c4\u03af\u03c4\u03b9\u03b4\u03b1 \u03b7 \u039f\u039d\u0391.<\/li>\n<\/ul>\n<p style=\"text-align: justify;\"><strong>\u0395\u03c1\u03b3\u03b1\u03c3\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03ac \u03ba\u03c1\u03b9\u03c4\u03ae\u03c1\u03b9\u03b1<\/strong><\/p>\n<ul style=\"text-align: justify;\">\n<li>\u0394\u03c5\u03c3\u03b1\u03bd\u03ac\u03bb\u03bf\u03b3\u03b7 \u03b1\u03bd\u03b1\u03b9\u03bc\u03af\u03b1 \u03bc\u03b5 \u03c4\u03b9\u03bc\u03ae \u03b1\u03b9\u03bc\u03bf\u03c3\u03c6\u03b1\u03b9\u03c1\u03af\u03bd\u03b7\u03c2 \u03c7\u03b1\u03bc\u03b7\u03bb\u03cc\u03c4\u03b5\u03c1\u03b7 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03c4\u03b9\u03bc\u03ae \u03c0\u03c1\u03bf \u03c4\u03b7\u03c2 \u03bc\u03b5\u03c4\u03ac\u03b3\u03b3\u03b9\u03c3\u03b7\u03c2.<\/li>\n<li>\u0395\u03bb\u03ac\u03c4\u03c4\u03c9\u03c3\u03b7 HbS (\u03b2\u03b9\u03bf\u03b4\u03b5\u03af\u03ba\u03c4\u03b7\u03c2 \u03ba\u03b1\u03c4\u03b1\u03c3\u03c4\u03c1\u03bf\u03c6\u03ae\u03c2 \u03ba\u03b1\u03b9 \u03c4\u03c9\u03bd \u03b4\u03c1\u03b5\u03c0\u03b1\u03bd\u03bf\u03ba\u03c5\u03c4\u03c4\u03ac\u03c1\u03c9\u03bd)<\/li>\n<li>\u0391\u03cd\u03be\u03b7\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03ad\u03bc\u03bc\u03b5\u03c3\u03b7\u03c2 \u03c7\u03bf\u03bb\u03b5\u03c1\u03c5\u03b8\u03c1\u03af\u03bd\u03b7\u03c2, LDH, CRP \u03ae \u03ba\u03b1\u03b9 \u03c4\u03b7\u03c2 \u03ba\u03c1\u03b5\u03b1\u03c4\u03b9\u03bd\u03af\u03bd\u03b7\u03c2<\/li>\n<li>\u0395\u03bb\u03ac\u03c4\u03c4\u03c9\u03c3\u03b7 \u03b1\u03c0\u03c4\u03bf\u03c3\u03c6\u03b1\u03c1\u03b9\u03bd\u03ce\u03bd<\/li>\n<li>\u03a3\u03c5\u03c7\u03bd\u03ac <em>\u0394\u0395\u039a \u03b5\u03bb\u03b1\u03c4\u03c4\u03c9\u03bc\u03ad\u03bd\u03b1<\/em><em>\u00a0<\/em><\/li>\n<\/ul>\n<p style=\"text-align: justify;\"><em>*\u038c\u03c4\u03b1\u03bd \u03c4\u03bf \u03c3\u03cd\u03bd\u03b4\u03c1\u03bf\u03bc\u03bf \u03b5\u03bc\u03c6\u03b1\u03bd\u03af\u03b6\u03b5\u03c4\u03b1\u03b9\u00a0 \u03c4\u03b7\u03bd \u03c0\u03c1\u03ce\u03c4\u03b7 \u03b2\u03b4\u03bf\u03bc\u03ac\u03b4\u03b1 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03bc\u03b5\u03c4\u03ac\u03b3\u03b3\u03b9\u03c3\u03b7 \u03c7\u03b1\u03c1\u03b1\u03ba\u03c4\u03b7\u03c1\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03c9\u03c2 \u03bf\u03be\u03b5\u03af\u03b1 \u03c5\u03c0\u03b5\u03c1\u03b1\u03b9\u03bc\u03cc\u03bb\u03c5\u03c3\u03b7 \u03bc\u03b5 \u03b1\u03bc.Coombs \u03c3\u03c5\u03bd\u03ae\u03b8\u03c9\u03c2 \u03b1\u03c1\u03bd\u03b7\u03c4\u03b9\u03ba\u03ae.<\/em><\/p>\n<p style=\"text-align: justify;\"><em>*\u038c\u03c4\u03b1\u03bd \u03b5\u03bc\u03c6\u03b1\u03bd\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03bc\u03b5\u03c4\u03ac \u03c4\u03b9\u03c2 7 \u03b7\u03bc\u03ad\u03c1\u03b5\u03c2 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03bc\u03b5\u03c4\u03ac\u03b3\u03b3\u03b9\u03c3\u03b7,\u00a0 \u03b8\u03c9\u03c1\u03b5\u03af\u03c4\u03b1\u03b9 \u03b5\u03c0\u03b9\u03b2\u03c1\u03b1\u03b4\u03c5\u03bd\u03cc\u03bc\u03b5\u03bd\u03b7 \u03c5\u03c0\u03b5\u03c1\u03b1\u03b9\u03bc\u03cc\u03bb\u03c5\u03c3\u03b7, \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03c3\u03c5\u03bd\u03b4\u03c5\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03bc\u03b5 \u0398\u03b5\u03c4\u03b9\u03ba\u03ae \u03b1\u03bc. Coombs \u03ba\u03b1\u03b9 \u03c4\u03bf \u03ad\u03ba\u03bb\u03bf\u03c5\u03bc\u03b1 \u03bd\u03b1 \u03b1\u03bd\u03b1\u03b4\u03b5\u03b9\u03ba\u03bd\u03cd\u03b5\u03b9 \u03b1\u03bb\u03bb\u03bf\u03b1\u03bd\u03c4\u03af\u03c3\u03c9\u03bc\u03b1 \u03b7 \u03ba\u03b1\u03b9 \u03c0\u03b1\u03bd\u03b1\u03bd\u03c4\u03af\u03c3\u03c9\u03bc\u03b1.<\/em><\/p>\n<h5 style=\"text-align: justify;\"><strong>\u0391\u039d\u03a4\u039c\u0395\u03a4\u03a9\u03a0\u0399\u03a3\u0397<\/strong><\/h5>\n<p>\u2022 \u0391\u03c0\u03bf\u03c6\u03c5\u03b3\u03ae \u03bc\u03b5\u03c4\u03b1\u03b3\u03b3\u03af\u03c3\u03b5\u03c9\u03bd \u03ba\u03b1\u03b8\u03ce\u03c2 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03c0\u03b9\u03b4\u03b5\u03b9\u03bd\u03ce\u03c3\u03bf\u03c5\u03bd \u03c4\u03b7\u03bd \u03b1\u03b9\u03bc\u03cc\u03bb\u03c5\u03c3\u03b7<br \/>\n\u2022 \u03a5\u03c0\u03bf\u03c3\u03c4\u03b7\u03c1\u03b9\u03ba\u03c4\u03b9\u03ba\u03ac \u03bc\u03ad\u03c3\u03b1 &#8211; \u03b9\u03c3\u03bf\u03b6\u03cd\u03b3\u03b9\u03bf \u03c5\u03b3\u03c1\u03ce\u03bd, \u03b4\u03b9\u03bf\u03cd\u03c1\u03b7\u03c3\u03b7 (\u03b1\u03c0\u03bf\u03c6\u03c5\u03b3\u03ae \u039f\u039d\u0391).<br \/>\n\u2022 \u0391\u03bd\u03bf\u03c3\u03bf\u03ba\u03b1\u03c4\u03b1\u03c3\u03c4\u03bf\u03bb\u03ae<br \/>\n&#8211; \u03a0\u03c1\u03b5\u03b4\u03bd\u03b9\u03b6\u03cc\u03bd\u03b7 1-2mg\/Kg<br \/>\n&#8211; \u03b7 \u03bc\u03b5\u03b8\u03c5\u03bb\u03c0\u03c1\u03b5\u03b4\u03bd\u03b9\u03b6\u03bf\u03bb\u03cc\u03bd\u03b7 0.5-1gr x 2-3 \u03b7\u03bc\u03ad\u03c1\u03b5\u03c2<br \/>\n&#8211; IVIG 0.4gr\/kg x 5 \u03b7\u03bc\u03ad\u03c1\u03b5\u03c2<br \/>\n\u2022 \u0395\u03c1\u03c5\u03b8\u03c1\u03bf\u03c0\u03bf\u03b9\u03b7\u03c4\u03af\u03bd\u03b7 \u03b5\u03bd\u03b4\u03b5\u03b9\u03ba\u03c4\u03b9\u03ba\u03ac 250-400U\/Kg x 3\/\u03b5\u03b2\u03b4\u03bf\u03bc\u03ac\u03b4\u03b1<br \/>\n&#8211; \u03c3\u03b5 \u03c0\u03b1\u03c1\u03b1\u03c4\u03b5\u03c4\u03b1\u03bc\u03ad\u03bd\u03b7 \u03b1\u03b9\u03bc\u03cc\u03bb\u03c5\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03b1\u03c0\u03b5\u03b9\u03bb\u03b7\u03c4\u03b9\u03ba\u03ae \u03b3\u03b9\u03b1 \u03c4\u03b7 \u03b6\u03c9\u03ae \u03b1\u03bd\u03b1\u03b9\u03bc\u03af\u03b1<br \/>\n&#8211; \u03c3\u03b5 \u03b1\u03bd\u03b8\u03b5\u03ba\u03c4\u03b9\u03ba\u03ad\u03c2 \u03c0\u03b5\u03c1\u03b9\u03c0\u03c4\u03ce\u03c3\u03b5\u03b9\u03c2 \u03c3\u03c4\u03b7\u03bd \u03b1\u03b3\u03c9\u03b3\u03ae \u03c0\u03c1\u03ce\u03c4\u03b7\u03c2 \u03b3\u03c1\u03b1\u03bc\u03bc\u03ae\u03c2<br \/>\n\u2022 Rituximab 100mg \u03b5\u03c9\u03c2 375mg\/m2 (\u03bc\u03b9\u03b1 \u03ad\u03c9\u03c2 4 \u03b4\u03cc\u03c3\u03b5\u03b9\u03c2 \u03b1\u03bd\u03ac \u03b2\u03b4\u03bf\u03bc\u03ac\u03b4\u03b1, \u03b1\u03bd\u03b1\u03bb\u03cc\u03b3\u03c9\u03c2 \u03b1\u03bd\u03c4\u03b1\u03c0\u03cc\u03ba\u03c1\u03b9\u03c3\u03b7\u03c2)<br \/>\n&#8211; \u03c3\u03b5 \u03c0\u03b1\u03c1\u03b1\u03c4\u03b5\u03c4\u03b1\u03bc\u03ad\u03bd\u03b7 \u03b1\u03b9\u03bc\u03cc\u03bb\u03c5\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03b1\u03c0\u03b5\u03b9\u03bb\u03b7\u03c4\u03b9\u03ba\u03ae \u03b3\u03b9\u03b1 \u03c4\u03b7 \u03b6\u03c9\u03ae \u03b1\u03bd\u03b1\u03b9\u03bc\u03af\u03b1 \u03b1\u03bd\u03b8\u03b5\u03ba\u03c4\u03b9\u03ba\u03ae \u03c3\u03c4\u03b1 \u03b1\u03bd\u03c9\u03c4\u03ad\u03c1\u03c9<br \/>\n\u2022 \u0395culizumab 900mg \u03b5\u03c6\u03ac\u03c0\u03b1\u03be (\u03b5\u03c0\u03b1\u03bd\u03ac\u03bb\u03b7\u03c8\u03b7 \u03c3\u03b5 7 \u03b7\u03bc\u03ad\u03c1\u03b5\u03c2 \u03b1\u03bd \u03c3\u03c5\u03bd\u03b5\u03c7\u03af\u03b6\u03b5\u03b9 \u03b7 \u03b1\u03b9\u03bc\u03cc\u03bb\u03c5\u03c3\u03b7)<br \/>\n\u2022 Tocilizumab \u03b5\u03c0\u03af \u03b1\u03c0\u03bf\u03c4\u03c5\u03c7\u03af\u03b1\u03c2 \u03c4\u03c9\u03bd \u03b1\u03bd\u03c9\u03c4\u03ad\u03c1\u03c9 (\u03bc\u03bf\u03bd\u03bf\u03ba\u03bb\u03c9\u03bd\u03b9\u03ba\u03cc \u03b1\u03bd\u03c4\u03af\u03c3\u03c9\u03bc\u03b1 \u03ad\u03bd\u03b1\u03bd\u03c4\u03b9 IL-6, \u03bc\u03b5\u03bc\u03bf\u03bd\u03c9\u03bc\u03ad\u03bd\u03b5\u03c2 \u03b1\u03bd\u03b1\u03c6\u03bf\u03c1\u03ad\u03c2 \u03c3\u03c4\u03b7 \u03b2\u03b9\u03b2\u03bb\u03b9\u03bf\u03b3\u03c1\u03b1\u03c6\u03af\u03b1)<\/p>\n<h5 style=\"text-align: justify;\"><strong>\u0392\u0399\u0392\u039b\u0399\u039f\u0393\u03a1\u0391\u03a6\u0399\u0391<\/strong><\/h5>\n<ol>\n<li style=\"text-align: justify;\">Madu AJ, Ugwu A O, Efobi C. Hyperhaemolytic syndrome in sickle cell disease: Clearing the cobwebs. Med Princ Pract 2021;30(3):236-43.<\/li>\n<li style=\"text-align: justify;\">Kasinathan G, Sathar J. Post-transfusion hyperhemolysis syndrome in a patient with beta thalassemia major. Clin Case Rep [Internet]. 2021 Jun;9(6):e04226. Available from: https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC8218318\/<\/li>\n<li style=\"text-align: justify;\">Patel I, Odak M, Douedi S, Alshami A, Upadhyaya VD, Hossain M, et al. Eculizumab as a treatment for hyper-haemolytic and aplastic crisis in sickle cell disease. Eur J Case Rep Intern Med [Internet]. 2021 Aug;8(10):002824. Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/34790624\/<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>Haema 2025; 16(1):25-26 \u0395\u03c5\u03c6\u03c1\u03bf\u03c3\u03cd\u03bd\u03b7 \u039d\u03bf\u03bc\u03b9\u03ba\u03bf\u03cd \u0391\u03b9\u03bc\u03b1\u03c4\u03bf\u03bb\u03cc\u03b3\u03bf\u03c2, \u0394\u03b9\u03b5\u03c5\u03b8\u03cd\u03bd\u03c4\u03c1\u03b9\u03b1 \u039d\u03a5 \u0391\u03b9\u03bc\u03bf\u03b4\u03bf\u03c3\u03af\u03b1\u03c2, \u03a4\u03bc\u03ae\u03bc\u03b1 \u0394\u03b9\u03b1\u03c4\u03b1\u03c1\u03b1\u03c7\u03ce\u03bd \u03c4\u03b7\u03c2 \u03a0\u03ae\u03be\u03b7\u03c2 \u03ba\u03b1\u03b9 \u0391\u03b9\u03bc\u03bf\u03c1\u03c1\u03bf\u03c6\u03b9\u03bb\u03b9\u03ba\u03ce\u03bd \u0391\u03c3\u03b8\u03b5\u03bd\u03ce\u03bd, \u0393\u039d\u0391 \u00ab\u0399\u03c0\u03c0\u03bf\u03ba\u03c1\u03ac\u03c4\u03b5\u03b9\u03bf\u00bb &nbsp; Full PDF |<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[166],"tags":[],"class_list":["post-2026","post","type-post","status-publish","format-standard","hentry","category-haema-2025-1"],"_links":{"self":[{"href":"https:\/\/haema-journal.gr\/index.php?rest_route=\/wp\/v2\/posts\/2026","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/haema-journal.gr\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/haema-journal.gr\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/haema-journal.gr\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/haema-journal.gr\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2026"}],"version-history":[{"count":2,"href":"https:\/\/haema-journal.gr\/index.php?rest_route=\/wp\/v2\/posts\/2026\/revisions"}],"predecessor-version":[{"id":2068,"href":"https:\/\/haema-journal.gr\/index.php?rest_route=\/wp\/v2\/posts\/2026\/revisions\/2068"}],"wp:attachment":[{"href":"https:\/\/haema-journal.gr\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2026"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/haema-journal.gr\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=2026"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/haema-journal.gr\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=2026"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}