{"id":631,"date":"2018-04-20T22:43:44","date_gmt":"2018-04-20T22:43:44","guid":{"rendered":"http:\/\/haema-journal.gr\/?p=631"},"modified":"2018-04-25T18:50:51","modified_gmt":"2018-04-25T18:50:51","slug":"the-role-of-autologous-stem-cell-transplantation-in-multiple-myeloma-in-the-era-of-novel-anti-myeloma-agents","status":"publish","type":"post","link":"https:\/\/haema-journal.gr\/?p=631","title":{"rendered":"The role of autologous stem cell transplantation in multiple myeloma in the era of novel anti-myeloma agents"},"content":{"rendered":"<p style=\"text-align: right;\"><em>Haema 2013; 4(3):220-227<\/em><\/p>\n<p>by Evangelos Terpos<sup>1<\/sup>, Dimitrios Christoulas<sup>2<\/sup>, Efstathios Kastritis<sup>1<\/sup><\/p>\n<p><sup>1<\/sup>Department of Clinical Therapeutics, Medical School, National and Kapodistrian University of Athens<br \/>\n<sup>2<\/sup>Department of Haematology, 251 General Air Force Hospital, Athens, Greece<\/p>\n<p style=\"text-align: right;\"><a href=\"http:\/\/haema-journal.gr\/PDF\/2013\/HAEMA_2013-220.pdf\" target=\"_blank\" rel=\"noopener\">Full PDF (in Greek)<\/a> | <a href=\"http:\/\/haema-journal.gr\/PDF\/2013\/HAEMA_2013-220.pdf\" target=\"_blank\" rel=\"noopener\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-390 size-full\" src=\"http:\/\/haema-journal.gr\/wp-content\/uploads\/2018\/02\/PDF-icon.jpg\" alt=\"\" width=\"36\" height=\"36\" \/><\/a><\/p>\n<p><!--more--><\/p>\n<h5><strong>Abstract<\/strong><\/h5>\n<p style=\"text-align: justify;\">In the era of conventional chemotherapy high dose melphalan followed by autologous stem cell transplantation (ASCT) immediately after induction chemotherapy was the treatment of choice in patients younger than 65 years old with multiple myeloma (MM). The integration of novel agents (thalidomide, bortezomib and lenalidomide) in induction regimens has resulted in increased survival of patients with MM and raises questions about the role of ASCT in the treatment of MM. This review attempts to give answers regarding the optimal induction therapy in patients who are candidates for ASCT, the need of ASCT as intensification treatment, the importance of achieving deep remission in relation to overall survival and the role of consolidation and maintenance therapy after ASCT.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Haema 2013; 4(3):220-227 by Evangelos Terpos1, Dimitrios Christoulas2, Efstathios Kastritis1 1Department of Clinical Therapeutics, Medical School, National and Kapodistrian University of Athens 2Department of Haematology, 251 General Air Force Hospital, Athens, Greece Full PDF (in Greek) |<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[46],"tags":[],"class_list":["post-631","post","type-post","status-publish","format-standard","hentry","category-haema-2013-3"],"_links":{"self":[{"href":"https:\/\/haema-journal.gr\/index.php?rest_route=\/wp\/v2\/posts\/631","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/haema-journal.gr\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/haema-journal.gr\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/haema-journal.gr\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/haema-journal.gr\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=631"}],"version-history":[{"count":4,"href":"https:\/\/haema-journal.gr\/index.php?rest_route=\/wp\/v2\/posts\/631\/revisions"}],"predecessor-version":[{"id":1034,"href":"https:\/\/haema-journal.gr\/index.php?rest_route=\/wp\/v2\/posts\/631\/revisions\/1034"}],"wp:attachment":[{"href":"https:\/\/haema-journal.gr\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=631"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/haema-journal.gr\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=631"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/haema-journal.gr\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=631"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}